| WHAT IS OSTEOARTHRITIS? Osteoarthritis
is a degenerative disease of the skeleton that affects the joints,
causing pain and loss of mobility. It is often known as “wear
and tear arthritis” because it is usually associated with
pain in the joints that have been under continued and repetitive
use for many years. It occurs in animals, as well as humans.
WHAT ARE THE SYMPTOMS IN MY PET?
The best way to diagnose your pet is to ask your vet. With that
in mind, here are some symptoms that may indicate your pet has osteoarthritis:
· Stiffness
· Reluctance to move
· Limping
· Difficulty in getting comfortable indicated by repeatedly
circling before lying down
· Sensitivity to touch
· Difficulty going up or down stairs
· Difficulty walking/change in gait
TREATMENT
If you don’t want to go the route of hard drugs like corticosteroids
and other anti-inflammatories that your vet would prescribe and
that have some nasty side-effects, there are a number of natural
remedies, including herbal medicines and nutritional supplements,
that are safe, effective treatments for arthritis. One of these
is Glucosamine, a natural substance that occurs in the body –
it not only treats the pain and improves mobility, but also appears
to stabilise cartilage degeneration in the joints.
WHAT IS GLUCOSAMINE?
Glucosamine is an amino-sugar, a compound consisting of an amino
acid and a sugar molecule. Synthesised from the simple sugar glucose
by every cell in the body, glucosamine is found in particularly
high concentrations in the cartilage and other connective tissues.
Glucosamine has many biological functions, one of the most important
being its role as a stimulant and precursor to the proteins that
form cartilage.
When a joint, particularly a weight-bearing joint, is in use, synovial
fluid is squeezed out of the cartilage and into the surrounding
joint capsule. As the pressure is released, the cartilage re-absorbs
the synovial fluid, much like a sponge.
This action enables the joint to take the impact and allows for
the smooth movement of the bones at the joint. Over time and with
repetitive use, the cartilage’s ability to hold and re-absorb
fluid is diminished and parts of the joint cartilage can wear away,
causing the pain and impared mobility associated with osteoarthritis.
GLUCOSAMINE HELPS REPAIR CARTILAGE
Glucosamine feeds cartilage and stimulates repair. It provides
one of the key building blocks of healthy cartilage, while also
encouraging the cartilage to repair itself by stimulating the process
that creates the moisture-holding cells. As the body ages, natural
glucosamine levels are depleted.
Supplementing the body’s natural stores with additional glucosamine
has been proven in clinical trails to reduce pain and increase mobility,
and to halt the progression of structural damage in joints. Some
trails have compared glucosamine with anti-inflammatory drugs and
shown to be as affective as drug treatments – but without
the side effects.
SUPPLEMENTING YOUR PET’S DIET WITH
GLUCOSAMINE
Glucosamine is not available from food sources in the diet.
There are two types of glucosamine – glucosamine sulphate
and glucosamine hydrochloride. Hydrochloride is a richer
form of glucosamine and only as little as 2.5ml/day (per 10kg body
weight) is required to gain full advantage.
Liquid Glucosamine Works: There is enough scientific
evidence now, and many thousands of reports from glucosamine users
to prove that glucosamine - in particular liquid glucosamine - really
does help to significantly relieve the pain of arthritis, to improve
cartilage, and to slow the progression of osteoarthritis.
The Bio-availability of Glucosamine: The bio-availability
of liquid glucosamine is much higher than that of solid-form glucosamine.
That is, the absorption rate of liquid glucosamine is significantly
higher than that of glucosamine taken in pills or capsule form.
Your pet’s body simply has a harder time absorbing pills than
liquids. (Humans, too.)
HOW MUCH SHOULD YOU GIVE YOUR PET?
Dosage is typically 2.5ml/10kg of body weight per day. It normally
takes several weeks before the benefits start to appear.
Here is a guide to how long a 500ml bottle will last:
| Cat approx 4kg |
16 months |
| Small Dog approx 10kg |
6.5 months |
| Medium Dog approx 20kg |
3.5 months |
| Large Dog approx 30kg |
2 months |
| Extra Large Dog approx 40kg |
50 days |
WHERE CAN YOU BUY
LIQUID GLUCOSAMINE FOR PETS?
Medtron Liquid Glucosamine is sold in 500ml bottles exclusively
by Pet Wares
Plus. You can purchase online for delivery anywhere in Australia
or internationally or ask your local vet.
Wholesale enquiries call the distributors TJP Group on (03) 9555
8425.
PRECAUTIONS
Animals with seafood allergies need to be aware that glucosamine
is manufactured commercially from the external skeletons of marine
crustaceans.
Some Facts About Osteoarthritis in Humans:
· Osteoarthritis is usually the result of constant wear
on the cartilage of a joint, and it develops with age.
· Osteoarthritis is associated with pain and swelling and
reduced mobility.
· More than 1.6 million Australians suffer from arthritis.
· Osteoarthritis is a leading cause of disability in the
elderly
· Glucosamine is a natural compound occurring in the cartilage.
· Glucosamine provides one of the key building blocks of
healthy cartilage and encourages the cartilage to repair itself.
· Clinical trials have shown that taking glucosamine reduces
pain and improves mobility.
· Glucosamine has been shown to be as effective as prescription
drugs but without the side effects.
· Regular gentle exercise helps to avoid the stiffening
often associated with arthritis.
References
Physicians Desk Reference for Nutritional Supplements. 2001. Thomson
Medical Economics.
Da Camara CC, Dowless GV. Glucosamine Sulphate for Osteoarthritis.
Ann Pharmacotherapy. 1998;32(5): 580-587.
Houpt JB, et al. Effect of Glucosamine Hydrochloride in the Treatment
of Pain of Osteoarthritis of the Knee. The Journal of Rheumatology.
1999;26:2423-2430.
Towheed TE , et al. Glucosamine therapy for treating osteoarthritis
(Cochrane Review). The Cochrane Library, Issue 3, 2003. Oxford:
Update Software.
McAlindon TE, LaValley MP, et al. Glucosamine and chondroitin for
treatment of osteoarthritis: a systematic quality assessment and
meta-analysis. JAMA. 2000; 283(11): 1469-1475.
Reginster JY, Gillot V, et al. Evidence of nutriceutical effectiveness
in the treatment of osteoarthritis. Current Rheumatology Reports.
2000; 2(6): 472-477.
© 2008 Medtron Pty Ltd. Sydney, NSW, Australia |